Shelterin complex and digestive system tumor
نویسندگان
چکیده
منابع مشابه
Shelterin
Schmutz and de Lange discuss the shelterin complex, which binds to mammalian telomeres and allows for the natural ends of chromosomes to be distinguished from sites of DNA damage.
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متن کاملShelterin: the protein complex that shapes and safeguards human telomeres
Added by telomerase, arrays of TTAGGG repeats specify the ends of human chromosomes. A complex formed by six telomere-specific proteins associates with this sequence and protects chromosome ends. By analogy to other chromosomal protein complexes such as condensin and cohesin, I will refer to this complex as shelterin. Three shelterin subunits, TRF1, TRF2, and POT1 directly recognize TTAGGG repe...
متن کاملShelterin: the protein complex that shapes and safeguards human telomeres.
Added by telomerase, arrays of TTAGGG repeats specify the ends of human chromosomes. A complex formed by six telomere-specific proteins associates with this sequence and protects chromosome ends. By analogy to other chromosomal protein complexes such as condensin and cohesin, I will refer to this complex as shelterin. Three shelterin subunits, TRF1, TRF2, and POT1 directly recognize TTAGGG repe...
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The digestive system is a way for nutrients from the outside environment to get to various parts of the body. At its simplest, the digestive system is a tube running from the mouth to the anus. This tube is similar to an assembly line, or more properly, a disassembly line. Its chief goal is to break down huge macromolecules (proteins,* fats, and starches) that cannot be absorbed as they are int...
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ژورنال
عنوان ژورنال: World Chinese Journal of Digestology
سال: 2012
ISSN: 2219-2859
DOI: 10.11569/wcjd.v20.i32.3124